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How to use it

inquiry

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We propose the optimal approach.

Localized gene expression analysis

Localized gene expression analysis
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Using a micro-tissue sampling device,
Collect and retrieve small tissue sections.
RNA-seq can also be performed on the collected tissue sections.

Xenium

Xenium
Xenium
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Subcellular resolution gene expression spatial analysis is possible.
Complex organizations, neighboring regions,
Understanding intercellular interactions,
Other spatial omics, organizations,
Integrated analysis of morphological information is possible.

The probes coated with fluorescent substances are hybridized,
Fluorescence is measured using an image-based method with Xenium Analyzer.

Suitable for fresh frozen sections or FFPE samples.

コンサルティング

Visium

Visium
Visium

サブセルラーの解像度の遺伝子発現空間解析が可能。
複雑な組織、近傍領域、細胞間相互作用を理解し、
他の空間的オミックス、組織、形態に関する
情報との統合解析が可能。

蛍光物質のついたプローブをハイブリダイズさせ、Xenium Analyzer​で蛍光を画像ベースで測定。

新鮮凍結切片またはFFPEサンプルに対応。

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インフォマティクス解析

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Chromium
(scRNA-seq)

Chromium
(scRNA-seq)
Chromium (scRNA-seq)

High-throughput single-cell analysis is possible.
Detailed analysis of cell populations and their state is possible.

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Phnobucycler

PacBio Revio
(Long read sequence)
Phnobucycler

Spatial single-cell analysis system in the tissue microenvironment

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Using frozen sections and FFPE sections
It is possible to perform fluorescent immunostaining of more than 50 proteins.
Imaging is possible with single-cell resolution.

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PacBio Revio (long-read sequencing)

Revio System
HiFi sequencing allows
Tens of thousands of base pairs of HiFi reads were obtained.
With outstanding sequencing accuracy,
Direct detection of DNA methylation, regardless of the context within the sequence.

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Reads with consistent coverage can be obtained.
Epigenetic analysis, repeat sequence analysis, and isoform analysis are possible. In addition,
Target sequencing is possible.

PacBio Revio
(Long read sequence)

PacBio Revio
(Long read sequence)

Results report

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concept

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早稲田大学空間オミックス解析研究拠点
Center for Spatial Omics Analysis Rearch (CESOAR)

513-121 Tsurumaki-cho, Waseda, Shinjuku-ku, Tokyo

CESOAR-support[at]list.waseda.jp

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